melanocytic nevi การใช้

• Melanocytic Nevi often grow proportionally to the body size as the child matures.
• Microscopically, congenital melanocytic nevi appear similar to acquired nevi with two notable exceptions.
• Skin manifestations can include scarring, eruptive melanocytic nevi, vulvovaginal stenosis, and dyspareunia.
• Neurocutaneous melanosis is associated with the presence of either giant congenital melanocytic nevi or non-giant nevi of the skin.
• It is estimated that neurocutaneous melanosis is present in 2 % to 45 % of patients with giant congenital melanocytic nevi.
• Therefore, it appears that malignant melanoma quite seldomly ( 1 % of cases ) has a melanocytic nevi as a precursor.
• This mutation has been detected in patients with congenital melanocytic nevi, as well as those with melanocytic tumors of the central nervous system.
• Neurocutaneous melanosis is characterized by the presence of congenital melanocytic nevi on the skin and melanocytic tumors in the leptomeninges of the central nervous system.
• As compared with a melanocytic nevus, congenital melanocytic nevi are usually larger in diameter and may have excess terminal hair, a condition called hypertrichosis.
• Fair-and red-haired people, persons with multiple atypical nevi or dysplastic nevi and persons born with giant congenital melanocytic nevi are at increased risk.
• He confirmed that the incidence of epidermolytic hyperkeratosis is higher in association with dysplastic nevi than in ordinary melanocytic nevi and may serve as a marker for NAD.
• As the lentigo maligna is often very large, it often merges with, or encompasses other skin tumors-such as lentigines, melanocytic nevi, and seborrheic keratosis.
• Melanocytic nevi and neoplasms are caused by either a proliferation of ( 1 ) melanocytes, or ( 2 ) nevus cells, a form of melanocyte that lack dendritic processes.
• Some melanocytic nevi, and melanoma-in-situ ( lentigo maligna ) have resolved with an experimental treatment, imiquimod ( Aldara ) topical cream, an immune enhancing agent.
• Data on the chances of transformation from melanocytic nevi to melanoma is controversial, but it appears that about 10 % of malignant melanomas have a precursor lesion, of which about 10 % are menanocytic nevi.
• The Classical ( 1990 ) definition uses the following criteria : 1 ) 100 or more melanocytic nevi, 2 ) one or more melanocytic nevi greater than or equal to 8mm in its largest diameter, and 3 ) one or more clinically atypical melanocytic nevi.
• The Classical ( 1990 ) definition uses the following criteria : 1 ) 100 or more melanocytic nevi, 2 ) one or more melanocytic nevi greater than or equal to 8mm in its largest diameter, and 3 ) one or more clinically atypical melanocytic nevi.
• The Classical ( 1990 ) definition uses the following criteria : 1 ) 100 or more melanocytic nevi, 2 ) one or more melanocytic nevi greater than or equal to 8mm in its largest diameter, and 3 ) one or more clinically atypical melanocytic nevi.
• The National Institutes of Health ( NIH ) Consensus 1992 definition, which is still controversial, requires a family history of melanoma, in addition to a large number of melanocytic nevi ( often greater than 50 ) and melanocytic nevi that present certain histological features.
• The National Institutes of Health ( NIH ) Consensus 1992 definition, which is still controversial, requires a family history of melanoma, in addition to a large number of melanocytic nevi ( often greater than 50 ) and melanocytic nevi that present certain histological features.